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Study identifier: NCT06157177 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Condition: Sciatica Acute · Lumbar Spinal Stenosis  ·  Sponsor: Primus Pharmaceuticals

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn if a modification to metaxalone 640 mg can reduce low back and leg pain. The participants will be 18 to 80 years old, healthy with newly occurring back or leg pain. The main question aims to compare a group taking active treatment and a group taking a look-alike substance containing no active treatment. All participants will answer questions on Day 1, before treatment, and on 7-day after treatment, about: * Amount and quality of pain * Interference with physical activity * Interference with sleep

This description comes directly from the study's public registry record.

Talk to the study team

S Sodhi  ·  205-202-0739  ·  simi@illumination.health

Always discuss trial participation with your own doctor first.

Locations (24)

East Alabama Arthritis CenterAuburn, Alabama, United StatesActive Not Recruiting
Sean Wollaston, MDValley Village, California, United StatesActive Not Recruiting
Arthritis and Osteoporosis CenterAventura, Florida, United StatesActive Not Recruiting
William Sunshine, MDBoca Raton, Florida, United StatesActive Not Recruiting
Robert Levin, MDClearwater, Florida, United StatesRecruiting
5. CZ RheumatologyCoral Springs, Florida, United StatesRecruiting
4. Palm Beach Rheumatology and WellnessJupiter, Florida, United StatesActive Not Recruiting
Family Arthritis CenterLoxahatchee Groves, Florida, United StatesActive Not Recruiting
Arthritis and Rheumatology Center of South FloridaMargate, Florida, United StatesActive Not Recruiting
Arthritis and Osteoporosis Treatment and ResearchCenterMiami, Florida, United StatesRecruiting
CZ RheumatologyMiami Beach, Florida, United StatesRecruiting
Bay Area RheumatologyOldsmar, Florida, United StatesRecruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06157177