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Study identifier: NCT06155032 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rescue Endovascular Therapy for Progressive Acute Mild Ischemic Stroke With Large Vascular Occlusion

Condition: Stroke, Ischemic · Cerebrovascular; Disorder, Occlusive  ·  Sponsor: First Affiliated Hospital of Wannan Medical College

PhaseNA
Planned participants272
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Endovascular therapy (EVT) added on best medical management is currently recommended in acute large vascular occlusion (LVO) stroke patients with National Institutes of Health Stroke Scale (NIHSS) score \>5. Thus, a sizeable fraction of patients with a minor stroke that do not undergo cerebrovascular screening may experience an early neurological deterioration (END) due to LVO, possibly leading to poor long-term functional outcome. However, whether these patients may still benefit from a rescue EVT is unknown, especially in a late window (\>24 hours). In this study, the investigators assume that best medical management plus EVT might be superior than best medical management alone in a late window for minor stroke patients who have experienced an LVO and END. The primary objective of the study was to establish the safety and efficacy of EVT in a late window for minor stroke patients in the anterior circulation who experienced an LVO and END.

This description comes directly from the study's public registry record.

Talk to the study team

Zhiming Zhou, PhD  ·  (++)86-(+)-553-5739543  ·  neuro_depar@hotmail.com

Kai Wang, PhD  ·  wangkai1964@126.com

Always discuss trial participation with your own doctor first.

Locations (7)

Fuyang People's HospitalFuyang, Anhui, ChinaRecruiting
First Affiliated Hospital of Anhui Medical UniversityHefei, Anhui, ChinaRecruiting
The first Hospital of Anhui University Of Science & TechnologyHuainan, Anhui, ChinaRecruiting
Huangshan City People's HospitalHuangshan City, Anhui, ChinaRecruiting
Wan Bei General Hospital of Wanbei Coal power GroupSuzhou, Anhui, ChinaRecruiting
The First Affiliated Hospital, Yijishan Hospital of Wannan Medical CollegeWuhu, Anhui, ChinaRecruiting
Xiangyang No.1 People's HospitalXiangyang, Hubei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06155032