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Study identifier: NCT06152809 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CIML NK Cells With Venetoclax for AML

Condition: Acute Myeloid Leukemia · Acute Myeloid Leukemia Recurrent · Leukemia  ·  Sponsor: Dana-Farber Cancer Institute

PhasePhase 1
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to test the safety and to explore the effectiveness of infusing cytokine- induced memory-like (CIML) natural killer (NK) cells in combination with Interleukin-2 (IL-2) and standard-of-care venetoclax as a treatment for Acute Myeloid Leukemia (AML). Names of the study therapies involved in this study are: * Lymphodepleting therapy with Fludarabine and Cyclophosphamide prior to CIML NK cell infusion * CIML NK (a cellular therapy) * IL-2 (a recombinant, human glycoprotein) * Venetoclax (a selective inhibitor of BCL-2 protein)

This description comes directly from the study's public registry record.

Talk to the study team

Evan Chen, MD  ·  (617) 632-1906  ·  evan_chen@dfci.harvard.edu

Rizwan Romee, MD  ·  (617) 632-3470  ·  rizwan_romee@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06152809