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Study identifier: NCT06150742 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

Condition: Acute Kidney Injury  ·  Sponsor: Talphera, Inc

PhaseNA
Planned participants70
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.

This description comes directly from the study's public registry record.

Talk to the study team

Nazneen Patel  ·  647-724-5709  ·  nazneen.patel@clinchoice.com

Chris Houchins  ·  chris.houchins@clinchoice.com

Always discuss trial participation with your own doctor first.

Locations (10)

University of California Los AngelesLos Angeles, California, United StatesRecruiting
AdventHealthOrlando, Florida, United StatesNot Yet Recruiting
Henry Ford HealthDetroit, Michigan, United StatesRecruiting
University of New MexicoAlbuquerque, New Mexico, United StatesRecruiting
Northwell HealthGreat Neck, New York, United StatesRecruiting
Mount SinaiNew York, New York, United StatesRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting
Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting
Baylor University Medical CenterDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06150742