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Study identifier: NCT06149585 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement

Condition: Edentulous Mouth · Periodontal Diseases · Periodontitis, Adult  ·  Sponsor: Case Western Reserve University

PhaseN/A
Planned participants12
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersYes

About this study

The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis; to evaluate if microbiome changes in relation to the used of different implant material/surface; and to assess the variance of the changes to determine the sample size for future longitudinal prospective studies.

This description comes directly from the study's public registry record.

Talk to the study team

Gian Pietro Schincaglia, DDS,PhD  ·  216-368-4412  ·  gxs486@case.edu

Elysha Pomerantz, DMD  ·  216-368-4412  ·  emp142@case.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Case Western Reserve University Department of PeriodonticsCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06149585