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Study identifier: NCT06147635 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prophylactic Tributyrin Supplementation in Acute Pancreatitis

Condition: Acute Pancreatitis  ·  Sponsor: St. Antonius Hospital

PhasePhase 2
Planned participants92
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate the possible effects of tributyrin supplementation in patients with a first episode of acute pancreatitis. The main question it aims to answer is: • The effect of oral tributyrin supplementation on the plasma endotoxin level Participants will be randomized between two groups: intervention and control group. They will receive: \- three times daily 4grams of micro-encapsulated granules of tributyrin, and the control group three times daily 4 grams of micro-encapsulated sunflower oil (i.e. placebo), for a total of 14 days In total 92 adult patients with a first episode of acute pancreatitis will be included.

This description comes directly from the study's public registry record.

Talk to the study team

Hannah Pauw, MD  ·  0883207051  ·  ha.pauw@antoniusziekenhuis.nl

Always discuss trial participation with your own doctor first.

Locations (2)

Reinier de Graaf GasthuisDelft, South Holland, NetherlandsNot Yet Recruiting
St. Antonius HospitalNieuwegein, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06147635