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Study identifier: NCT06146946 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)

Condition: Rectal Cancer  ·  Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

PhaseNA
Planned participants1384
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn about whether it is safe to omit dissection of the No.253 lymph nodes in mid and low rectal cancer surgery. The main question it aims to answer is that if it is possible to achieve the same long-term survival with and without the dissection of the No.253 lymph node in mid and low rectal cancer surgery. Participants will underwent laparoscopic rectal radical resection with or without the dissection of the No.253 lymph node.

This description comes directly from the study's public registry record.

Talk to the study team

Mingguang Zhang, Dr.  ·  +8613261967603  ·  zmgslimshady@163.com

Qian Liu, Dr.  ·  13601008906  ·  fcwpumch@163.com

Always discuss trial participation with your own doctor first.

Locations (8)

Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting
China-Japan Friendship HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Beijing Cancer HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Chinese PLA General HospitalBeijing, Beijng, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy of Medical SciencesBeijing, Chaoyang District, ChinaRecruiting
Ruijin Hospital, Shanghai Jiaotong University School of MedicineShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting
West China Hospital Sichuan UniversityChengdu, Sichuan, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06146946