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Study identifier: NCT06143306 Synced from ClinicalTrials.gov · July 28, 2026
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Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

Condition: Total Shoulder Arthroplasty  ·  Sponsor: University of Minnesota

PhasePhase 4
Planned participants110
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The use of ISB in patients undergoing total shoulder arthroplasty (TSA) is the gold standard and results in significantly reduced pain scores and opioid use. However, patients still have pain and the majority require opioids postoperatively as the interscalene block (ISB) doesn't cover all of the dermatomes impacted during TSA. A pectoserratus block typically provides coverage to additional dermatomes that are impacted during TSA. Currently ISB is performed for every patient and perform a pectoserratus block to a portion of our patients undergoing TSA. The purpose of the study is to determine if the addition of the pectoserratus block to the ISB will results in improvement in pain control and decrease in opioid use, among patients undergoing TSA. This is a randomized prospective controlled trial. All patients undergoing total shoulder arthroplasty or reverse total shoulder arthroplasty aged 18-85 will be considered eligible for the study. Participants will be randomized to one of 2 treatment groups. Group 1 will receive an ultrasound guided pectoserratus block with 25 mL of 0.25% bupivacaine. Group 2 will be the control and receive an ultrasound guided pectoserratus block with 25 mL of saline. The drug will be administered by the anesthesiologist in-charge of the participant's care or an anesthesiologist who is a part of the study team.

This description comes directly from the study's public registry record.

Talk to the study team

Candace Nelson  ·  612-625-7116  ·  nelso377@umn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06143306