Condition: Ventricular Tachycardia · Ischemic Cardiomyopathy · Sponsor: Rush University Medical Center
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a variable incorporating power delivery in its formula and combining it with CF and time in a weighted equation which aims at allowing for a more precise estimation of lesion depth and quality when ablating VAs. AI guidance has previously been shown to improve outcomes in atrial and ventricular ablation in patients with premature ventricular complexes (PVC). However research on outcomes following AI-guidance for VT ablation specifically in patients with structural disease and prior myocardial infarction remains sparse. The investigators aim at conducting the first randomized controlled trial testing for the superiority of an AI-guided approach regarding procedural duration.
This description comes directly from the study's public registry record.
Alexander Mazur, MD · 312-942-5020 · alexander_mazur@rush.edu
Always discuss trial participation with your own doctor first.
| Rush University Medical Center | Chicago, Illinois, United States | Recruiting |
| Mass General Brigham and Women's Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| Medical University of Michigan | Ann Arbor, Michigan, United States | Not Yet Recruiting |
| Mayo Clinic | Rochester, Minnesota, United States | Not Yet Recruiting |
| Medical University of South Carolina | Charleston, South Carolina, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06138873