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Study identifier: NCT06138587 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Condition: Acute Myeloid Leukemia · Leukemia · Leukemia, Myeloid  ·  Sponsor: Dana-Farber Cancer Institute

PhasePhase 1
Planned participants15
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to test the safety and efficacy of cytokine induced memory-like (CIML) natural killer (NK) cells expanded with Interleukin-2 (IL-2) at preventing relapse in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or MDS and myeloproliferative neoplasm (MPN) overlap syndrome after a standard-of-care stem cell transplant. Names of the study therapies involved in this study are: * CIML NK cells intravenous infusion (cellular therapy) * Subcutaneous Interleukin-2 (recombinant, human glycoprotein)

This description comes directly from the study's public registry record.

Talk to the study team

Roman Shapiro, MD  ·  617-632-3470  ·  roman_shapiro@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06138587