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Study identifier: NCT06133842 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State

Condition: Perioperative/Postoperative Complications · Postoperative Cognitive Dysfunction · Postoperative Delirium  ·  Sponsor: Beth Israel Deaconess Medical Center

PhaseN/A
Planned participants100
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this observational study is to learn the how to determine the mean arterial pressure(MAP) or blood pressure level to be maintained during non-cardiac surgery for optimal brain health in patients above the age of 60 undergoing major non-cardiac surgery. The main question\[s\] it aims to answer are: * Is there a way to tailor the blood pressure to be maintained in such patients during surgery for optimal brain health using non-invasive monitors that check the brains electrical activity, the electroencephalogram(EEG) monitor, and the brain's blood oxygen levels, the cerebral oximetry(CO) monitor? * How much does this optimal blood pressure level vary between patients? Participants will be asked to: * Complete a questionnaire at the time they enroll into the study, as well as a daily questionnaire to help determine their level of thinking and brain health. This questionnaire will be administered by a member of the study team. * They will also have an EEG and CO monitoring sticker placed on their foreheads. This will be connected to a monitor that will collect this data just before, during, and after their surgery. The data collected through these monitors will help us with our study goals.

This description comes directly from the study's public registry record.

Talk to the study team

Samir M Kendale, MD  ·  (617) 975-8500  ·  skendale@bidmc.harvard.edu

Zaid Hussain, MBBS  ·  zhussai1@bidmc.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Beth Israel Deaconess Medical CenterBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06133842