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Study identifier: NCT06130995 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Condition: Androgen Deprivation Therapy · Locally Advanced Prostate Cancer  ·  Sponsor: University of Oklahoma

PhasePhase 1
Planned participants46
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to test how effective and safe it is to use a combination of two medications, relugolix and enzalutamide, in patients with advanced prostate cancer. We want to see if this combination can help improve the chances of curing the cancer and make the patients live longer without the cancer getting worse. The main questions we want to answer in this study are: * Can using relugolix and enzalutamide together help increase the chances of curing high-risk advanced prostate cancer? * Does this combination treatment help patients live longer without their cancer getting worse? Participants in this study will be asked to take relugolix and enzalutamide as part of their cancer treatment. They will also undergo Radiation Therapy or prostatectomy, which are standard treatments for this type of cancer.

This description comes directly from the study's public registry record.

Talk to the study team

lead onco nurse, RN  ·  405-271-8777  ·  SCCIITOffice@ouhsc.edu

Kelly Stratton, MD  ·  (405) 271-6900  ·  Kelly-Stratton@ouhsc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Stephenson Cancer Center at OU Health, University of Oklahoma Health Sciences Center (SCC-OUHSC)Oklahoma City, Oklahoma, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06130995