● Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Condition: Transthyretin Amyloidosis (ATTR) With Cardiomyopathy · Sponsor: Intellia Therapeutics

PhasePhase 3

Planned participants1200

Who can joinAll sexes, 18 Years to 90 Years

Healthy volunteersNo

About this study

To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Manager at Intellia · 1-857-285-6200 · medicalinformation@intelliatx.com

Always discuss trial participation with your own doctor first.

Locations (132)

University of Arizona	Tucson, Arizona, United States	Recruiting
Cedars-Sinai Medical Center	Los Angeles, California, United States	Recruiting
Western Greater Los Angeles VA Medical Center	Los Angeles, California, United States	Recruiting
Stanford University	Palo Alto, California, United States	Recruiting
University of California, San Diego (UCSD) - Medical Center	San Diego, California, United States	Recruiting
University of Colorado Denver	Denver, Colorado, United States	Recruiting
Yale University School of Medicine	New Haven, Connecticut, United States	Recruiting
MedStar Washington Hospital Center - MedStar Heart and Vascular Institute	Washington D.C., District of Columbia, United States	Recruiting
Mayo Clinic - Jacksonville	Jacksonville, Florida, United States	Recruiting
Cleveland Clinic of Florida	Weston, Florida, United States	Recruiting
Emory University School of Medicine	Atlanta, Georgia, United States	Recruiting
Northwestern University	Chicago, Illinois, United States	Recruiting

+ 120 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06128629