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Study identifier: NCT06123715 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

Condition: Chronic Pain · Knee Pain Chronic · Post Operative Pain  ·  Sponsor: University Health Network, Toronto

PhasePhase 2
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase II Multicentre, pilot, parallel-group, blinded, 1:1 randomized controlled trial to determine the feasibility of conducting a larger definitive trail of using vitamin C to reduce persistent pain in patients undergoing total knee arthroplasty surgery.

This description comes directly from the study's public registry record.

Talk to the study team

James Khan, MD  ·  416-340-4800  ·  James.Khan@medportal.ca

Nour Ayach  ·  (416) 340 4800  ·  Nour.Ayach@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Sunnybrook - Holland CentreToronto, Ontario, CanadaRecruiting
Mount Sinai HospitalToronto, Ontario, CanadaRecruiting
Toronto Western HospitalToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06123715