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Study identifier: NCT06120582 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

Condition: Hemophilia B  ·  Sponsor: Biocad

PhasePhase 1/Phase 2
Planned participants28
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this multicenter, two-stage, open-label study is to investigate the safety, immunogenicity, and efficacy of ANB-002 in subjects with hemophilia В. The study will have a dose-escalation design with elements of phase I/II seamless adaptive design.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Eremeeva, MD PhD  ·  +7 (812) 380 49 34  ·  eremeevaav@biocad.ru

Always discuss trial participation with your own doctor first.

Locations (17)

Republican Scientific and Practical Center for Radiation Medicine and Human EcologyHomyel, BelarusRecruiting
Minsk Scientific and Practical Center for Surgery, Transplantology and HematologyMinsk, BelarusRecruiting
State Autonomous Institution for Healthcare "Chelyabinsk Regional Clinical Hospital"Chelyabinsk, RussiaRecruiting
State budgetary healthcare institution Leningrad Regional Clinical HospitalGatchina, RussiaRecruiting
Kuzbass Clinical Hospital named after S.V. BelyaevKemerovo, RussiaRecruiting
Federal State Budgetary Organization of Science "Kirov Research Institute of Hematology and Blood Transfusions of Federal Medical Biological agency"Kirov, RussiaRecruiting
Federal State Budgetary Institution "National Medical Research Centre for Hematology" of the Ministry of Health of Russian Federation (Department of Clinical Diagnostics for Hematology and Hemostasis Disorders)Moscow, RussiaRecruiting
Federal State Budgetary Institution "National Medical Research Centre for Hematology" of the Ministry of Health of Russian Federation (Department of Traumatology and Reconstructive and Restorative Orthopedics for Patients with Hemophilia)Moscow, RussiaRecruiting
Federal Budgetary Institution "Moscow City Clinical Hospital named after S. P. Botkin"Moscow, RussiaRecruiting
LLC "Medis"Nizhny Novgorod, RussiaRecruiting
State Novosibirsk Regional Clinical HospitalNovosibirsk, RussiaRecruiting
Russian Research Institute of Hematology and Transfusiology Federal State Institution of Federal Medical and Biological AgencySaint Petersburg, RussiaRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06120582