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Study identifier: NCT06118697 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Feasibility of Aerodigestive Stimulation Therapy Trial

Condition: Feeding Disorder Neonatal  ·  Sponsor: Sudarshan Jadcherla

PhaseNA
Planned participants40
Who can joinAll sexes, 1 Day to 8 Months
Healthy volunteersNo

About this study

The goal of this study is to demonstrate safety, feasibility, and efficacy of a novel pharyngo-esophageal stimulation technique in restoring aerodigestive and swallowing functions in select infants at-risk for chronic gavage tube feeding or gastrostomy. The main aims are: * To provide consistent activation of deglutition (the process of swallowing), swallowing-airway interactions, and peristalsis in order to decrease the risk of home tube feeding. * To examine whether physical and manometric evidence-guided interventions and biofeedback will improve compliance, minimize parental stress, and increase satisfaction and perceived self-confidence with infant feeding. Participants will have weekly pharyngo-esophageal stimulation guided by High Resolution Impedance Manometry (HRIM) for 4 weeks or until discharge, oral nutritive stimulation of at least 5 mL of prescribed milk with each feed, and weekly parental education and feedback regarding feeding progress.

This description comes directly from the study's public registry record.

Talk to the study team

Erika K Osborn  ·  6143556667  ·  erika.osborn@nationwidechildrens.org

Patty Luzader  ·  6143556627  ·  patty.luzader@nationwidechildrens.org

Always discuss trial participation with your own doctor first.

Locations (1)

Nationwide Children's HospitalColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06118697