Condition: Diabetes Mellitus Type 2, Diabetes Mellitus Type 1 · NAFLD - Nonalcoholic Fatty Liver Disease · PreDiabetes · Sponsor: Dasman Diabetes Institute
Kuwait and the Gulf Region lack large longitudinal studies that identify risk factors dictating the onset of prediabetes and the progression to diabetes. The Kuwait Diabetes Epidemiology Program (KDEP), previously carried out at Dasman Diabetes Institute, was designed to develop a research dataset providing a random sampling of the Kuwaiti population. The dataset contained primarily epidemiology data for healthy, prediabetic and diabetic individuals; and was designed to serve as a resource for research and prevention programs on obesity, diabetes, and metabolic syndrome. The KDEP data supported research studies at DDI to delineate risk factors for metabolic disease from the views of genetics, biochemistry, immunology and epidemiology. One of the main limitations of the KDEP study was that it only captured a cross-sectional view of the participants in terms of diabetes status as well as lack of extensive phenotyping. In the current study, the investigators aim to perform a follow up on the non-diabetic KDEP cohort participants to enrich it with detailed physiological, genetic, biochemical and environmental data and thereby to establish an association between the development of diabetes and multidimensional risk factors. the investigatorswill also recruit family members of the KDEP and RA2010-005 participants as well as others with family history of diabetes to better identify familial patterns in risk factors. The outcome of this effort will immediately serve as a scientific b…
This description comes directly from the study's public registry record.
Mohamed Abu-farha, PhD · +96560660804 · mohamed.abufarha@dasmaninstitute.org
Fahd Al-Mulla, MD, PhD · 2224 2999 · fahd.almulla@dasmaninstitute.org
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| Dasman Diabetes Institute | Kuwait City, Kuwait | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06115876