Condition: Acute Exacerbation of Chronic Obstructive Pulmonary Disease · Hypercapnic Acidosis · Respiratory Failure With Hypercapnia · Sponsor: University Hospital, Montpellier
The purpose of this study is to determine whether nasal high flow is non inferior to non invasive ventilation (NIV) in the early treatment of patients with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) and hypercapnic acidosis in the emergency department (ED). After obtaining informed consent, participants will be randomly assigned to receive either nasal high flow or non invasive ventilation (NIV, reference treatment) as respiratory support. Researchers will compare both respiratory support groups to see if their blood gas analysis and respiration return to normal ranges.
This description comes directly from the study's public registry record.
Mustapha Sebbane, MD, PhD · +33 (4) 67 33 85 76 · m-sebbane@chu-montpellier.fr
Sophie LEFEBVRE, PhD · +33 (4) 67 33 85 76 · s-lefebvre@chu-montpellier.fr
Always discuss trial participation with your own doctor first.
| Montpellier University Hospital | Montpellier, Montepllier, France | Recruiting |
| Centre hospitalier universitaire de Nimes | Nîmes, France | Not Yet Recruiting |
| Centre Hospitalier Universitaire de Poitiers | Poitiers, France | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06114667