Condition: Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) v8 · Anatomic Stage II Breast Cancer AJCC v8 · Anatomic Stage III Breast Cancer AJCC v8 · Sponsor: Jonsson Comprehensive Cancer Center
This phase II trial tests how well fisetin and exercise works in preventing frailty in breast cancer survivors. Fisetin is a natural substance found in strawberries and other foods and is available as a nutritional supplement. Nutritional supplements may be useful in eliminating cells that have undergone a process called senescence. Senescence is when a cell ages and permanently stops dividing but does not die. Over time, large numbers of these cells build up in tissues throughout the body and can release harmful substances that cause inflammation and damage nearby healthy cells. Giving fisetin may eliminate senescent cells in patients with breast cancer undergoing physical activity.
This description comes directly from the study's public registry record.
Mina S. Sedrak, MD · 310-825-3181 · msedrak@mednet.ucla.edu
Kelly Synold · 424-440-3877 · ksynold@mednet.ucla.edu
Always discuss trial participation with your own doctor first.
| UCLA Health Cancer Care in Alhambra | Alhambra, California, United States | Recruiting |
| UCLA Health Beverly Hills Primary & Specialty Care | Beverly Hills, California, United States | Recruiting |
| UCLA Health Burbank Primary & Specialty Care | Burbank, California, United States | Recruiting |
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | Recruiting |
| UCLA Health Primary Care in Marina del Rey | Marina del Rey, California, United States | Recruiting |
| UCLA Health Primary Care in Pasadena | Pasadena, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06113016