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Study identifier: NCT06107920 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy

Condition: Colon Cancer  ·  Sponsor: University Hospital, Rouen

PhasePhase 3
Planned participants232
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to determine whether chemotherapy prior to tumor removal (neoadjuvant chemotherapy), in patients undergoing treatment for colon cancer in occlusion (CCO), would improve the rate of patients able to benefit from "optimal" treatment, i.e. complete treatment (including all neoadjuvant and adjuvant chemotherapy cures). This new strategy, which would combine chemotherapy before surgery and possibly post-operatively (depending on tumor analysis), could improve the prognosis of occluded colon cancers by treating circulating micrometastases and/or inducing a reduction in tumor size, thereby increasing the rate of complete resection.

This description comes directly from the study's public registry record.

Talk to the study team

Valérie Bridoux  ·  0232881347  ·  valerie.bridoux@chu-rouen.fr

Julie Rondeaux, PhD  ·  0232885427  ·  julie.rondeaux@chu-rouen.fr

Always discuss trial participation with your own doctor first.

Locations (28)

Chu AmiensAmiens, FranceRecruiting
Chr BeauvaisBeauvais, FranceRecruiting
Chru BesanconBesançon, FranceRecruiting
Aphp AvicenneBobigny, FranceRecruiting
CHU CAENCaen, FranceRecruiting
Aphp Antoine BeclereClamart, FranceRecruiting
Chu ColmarColmar, FranceRecruiting
Chu DijonDijon, FranceRecruiting
Chu GrenobleGrenoble, FranceRecruiting
Aphp Kremlin BicetreLe Kremlin-Bicêtre, FranceRecruiting
Chru LilleLille, FranceRecruiting
Chru LilleLille, FranceRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06107920