Condition: Advanced Non Small Cell Lung Cancer · Sponsor: CellSight Technologies, Inc.
This pilot study uses \[18F\]F AraG PET imaging to evaluate the immunological response to checkpoint inhibitor therapy (CkIT) in patients with advanced NSCLC tumors. The study's main objectives are to quantify the change in \[18F\]F AraG PET signal before and while on CkIT therapy and to correlate this change in \[18F\]F AraG PET signal with radiographic response. To explore these objectives, eligible subjects will undergo pre- and on - CkIT treatment \[18F\]F AraG PET/CT scans, and will be followed up for 12 months for assessment of radiographic and clinical outcomes. This study is a single-site, open label, non randomized, single arm pilot trial. Patients and care providers will not be blinded to any part of the study.
This description comes directly from the study's public registry record.
Amy Mundisev · 319-356-1445 · amy-mundisev@uiowa.edu
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| University of Iowa Hospitals and Clinics | Iowa City, Iowa, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06107374