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Study identifier: NCT06105788 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

Condition: Knee Osteoarthritis · Knee Pain Chronic · Central Pain Syndrome  ·  Sponsor: University of Texas, El Paso

PhaseNA
Planned participants60
Who can joinAll sexes, 45 Years to 90 Years
Healthy volunteersYes

About this study

The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).

This description comes directly from the study's public registry record.

Talk to the study team

Kosaku Aoyagi, PhD  ·  9157478215  ·  kaoyagi@utep.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Texas at El PasoEl Paso, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06105788