Condition: Hypertension in Pregnancy · Hypertension · Pregnancy · Sponsor: University of Sao Paulo
High blood pressure during pregnancy poses significant risks to both the mother and baby. A combination of factors, including advancing maternal age, rising obesity rates, and metabolic health issues, have amplified the prevalence of this condition. While conventional medicines are available, safety during pregnancy remains a concern. Recent studies suggest that inorganic nitrate might be a safer alternative. The power of nitrate lies in its ability to stimulate the body's production of a compound that aids in dilating and relaxing blood vessels. Preliminary studies conducted on mice and a select group of pregnant women have yielded encouraging results. Early tests indicated that after consuming inorganic nitrate, there was a reduction in blood pressure and an improvement in the health of the mother's uterine artery-a vital vessel responsible for nourishing the fetus. Our study aims to investigate the effects of inorganic nitrate supplementation on pregnant women from the start of their pregnancy and continuing it throughout their term. If our findings are positive, it could revolutionize how we approach blood pressure management during pregnancy, paving the way for healthier futures for both mothers and babies.
This description comes directly from the study's public registry record.
Ricardo C Cavalli, Dr · +55166021000 · rcavalli@fmrp.usp.br
Priscila O Barbosa, Dr · +5531971349289 · barbosapo@usp.br
Always discuss trial participation with your own doctor first.
| Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP | Ribeirão Preto, São Paulo, Brazil | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06105775