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Study identifier: NCT06103201 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury

Condition: Traumatic Brain Injury · Subarachnoid Hemorrhage  ·  Sponsor: University of Maryland, Baltimore

PhasePhase 1
Planned participants15
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

The purpose of this study is to examine the safety and feasibility of using hyperpolarized metabolic MRI to study early brain metabolism changes in subjects presenting with head injury and suspected non-penetrating traumatic brain injury (TBI). This study will also compare HP pyruvate MRI-derived metrics in TBI patients with healthy subjects as well as Subarachnoid hemorrhage (SAH) patients to better understand if metabolic Magnetic resonance imaging scan (MRI) can improve our ability to diagnose a TBI. The FDA is allowing the use of hyperpolarized \[1-13C\] pyruvate (HP 13C-pyruvate) in this study. Up to 15 patients (5 with TBI, 5 with SAH, and 5 healthy volunteers) may take part in this study at the University of Maryland, Baltimore (UMB).

This description comes directly from the study's public registry record.

Talk to the study team

Rosy Linda Njonkou Tchoquessi  ·  410-706-0943  ·  rnjonkou@som.umaryland.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Maryland BaltimoreBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06103201