Condition: Blood Transfusion · Sponsor: Università degli Studi di Ferrara
In critically ill patients, optimized strategies for red blood cells transfusion (RBCT) are still controversial. Most recent guidelines suggest that clinical practice in ICU setting should follow a restrictive approach to RBCT (i.e., hemoglonim level \< 7.0 g/dL).In our previous study, oxygen extraction ratio (O2ER) has shown good performance as a marker to identify the correct timing for RBCT, potentially affecting 90-day mortality in non-bleeding, critically ill patients \[11\]. Moreover, our data suggested that an individualized strategy for RBCT may reduce the incidence of acute kidney injury (AKI), which is possibly related to a better delivery of oxygen and organ perfusion.
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| Hospital Erasme | Brussels, Belgium | Not Yet Recruiting |
| Università di Ferrara | Ferrara, Ferrara, Italy | Recruiting |
| Università di Perugia | Perugia, Italy, Italy | Recruiting |
| Anestesia e Rianimazione Cardio-Toraco-Vascolare | Siena, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06102590