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Study identifier: NCT06101511 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Driving Pressure During General Anesthesia for Minimally Invasive Abdominal Surgery (GENERATOR)

Condition: Postoperative Complications · Surgery  ·  Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

PhaseNA
Planned participants1806
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this international multicenter, patient and outcome-assessor blinded randomized controlled trial is to determine whether the application of an individualized high Positive End Expiratory Pressure (PEEP) strategy with recruitment maneuvers, aiming at avoiding an increase in the driving pressure during intraoperative ventilation, protects against the development of postoperative pulmonary complications in patients undergoing minimally invasive abdominal surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Tom Vermeulen, MD  ·  + 31 020 566 2533  ·  t.d.vermeulen@amsterdamumc.nl

Galina Dorland, MD  ·  g.dorland@amsterdamumc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Amsterdam University Medical CenterAmsterdam, Noordholland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06101511