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Study identifier: NCT06100822 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Managing Chronic Tendon Pain by Metformin

Condition: Tendinopathy · Chronic Pain · Achilles Tendinopathy  ·  Sponsor: James Wang

PhasePhase 1
Planned participants40
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

The purpose of the current exploratory clinical trial is to determine the effect of oral ingestion of metformin (OIM) in non-diabetic patients with chronic Achilles tendon pain. The trial has two aims; 1) to assess the effects of OIM treatment on tendon pain, and 2) to determine the effects of OIM capsules on tendon healing and repair. Twenty participants will be treated with metformin capsules for 16 weeks combined with a home exercise program. A comparison group of 20 participants will be treated with placebo tablets along with home exercise program.

This description comes directly from the study's public registry record.

Talk to the study team

James H Wang, PhD  ·  4126489102  ·  wanghc@pitt.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06100822