Condition: Constipation - Functional · Constipation · Constipation by Outlet Obstruction · Sponsor: Guy's and St Thomas' NHS Foundation Trust
Rectal irrigation, which is the introduction of warm tap water through the anal canal into the rectum to initiate defaecation, is recommended to be considered in patients with chronic constipation, which is refractory to conservative measures such as lifestyle modification, laxatives, nurse-led bowel retraining programmes which focuses on bio-feedback as well as psychosocial support. Two systems of rectal irrigation are available based on volume delivered, low and high volume. It is unknown if one type of irrigation is superior to the other and whether one type has better outcomes in patients with a particular pathology. Therefore, a comparison is required between the two types of irrigation to assess their acceptability as a therapy and response rates in patients with chronic constipation secondary to difficulty emptying rectum. This trial/research aims to compare low-volume rectal irrigation with high-volume rectal irrigation in patients with chronic constipation secondary to disorders of difficulty emptying rectum. The main questions it aims to answer are: * if one type of rectal irrigation is superior to the other * whether one type of rectal irrigation has better outcomes in patients with a particular pathology on pelvic floor ultrasound * assess the acceptability and response rates to rectal irrigation. Participants upon recruitment will be allocated to either low-volume rectal irrigation or high volume rectal irrigation groups. This will purely be by chance where…
This description comes directly from the study's public registry record.
Tanzeela Gala, FCPS-Surgery · 07496288119 · tanzeela.gala@gstt.nhs.uk
Alison Hainsworth, FRCS · alison.hainsworth@gstt.nhs.uk
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| St Thomas' Hospital | London, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06100055