Condition: Multiple Myeloma · Frailty · Sponsor: FengYan Jin
Frailty is dynamic and confers poor outcomes in elderly patients with newly diagnosed multiple myeloma (NDMM), mainly because of the high prevalence of treatment discontinuation due to intolerability. We designed a multi-center prospective study (DynaFiT) based on our real-life practice to evaluate the feasibility and benefits of a dynamic frailty-tailored therapy in elderly patients with different fitness/frailty statuses. Since Dara-based treatment have recently become the new standard regimens, in this amendment of the study, daratumumab added to VRd is recommended as induction therapy regimen.
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| The First Hospital of Jilin University | Changchun, Jilin, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06099912