Condition: Digestive System Cancers · Sponsor: Peking University Cancer Hospital & Institute
The study is an interventional phase II clinical trial aiming to evaluate the efficacy and safety of KN046, a PD-L1 and CTLA-4 bispecific antibody, in combination with regorafenib or apatinib for microsatellite instability-high digestive system cancers resistant to PD-1/PD-L1 blockade. KN046 plus regorafenib will be given for patients with colorectal cancers, and KN046 plus apatinib will be given for patients with gastric cancers (including esophageal-gastric junction cancers) and other kinds of digestive system cancers.
This description comes directly from the study's public registry record.
Zhenghang Wang · 01088196561 · zhenghang_wang@bjmu.edu.cn
Ting Xu · 18201137836 · xtlmhxt@163.com
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| Peking University Cancer Hospital | Beijing, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06099821