Condition: NSCLC · Sponsor: Base Therapeutics (Shanghai) Co., Ltd.
This study assesses the safety and efficacy of NK510 combined with PD-(L)1 inhibitors for relapsed/refractory advanced NSCLC, with two administration routes: intravenous infusion and intrapleural perfusion for malignant pleural effusion. Eligible patients need confirmed measurable lesions; intravenous cohort requires EGFR/ROS1/ALK negativity and disease progression after PD-(L)1 inhibitor treatment, while intrapleural cohort accepts targeted therapy-resistant patients with ≥500ml pleural effusion, and the treatment's safety, efficacy and immune microenvironment changes will be evaluated.
This description comes directly from the study's public registry record.
Jun Yan, PhD · +86 186 2166 8515 · yanjun@basetherapeutics.com
Tangfeng Lv · +86 139 5201 6932 · bairoushui@163.com
Always discuss trial participation with your own doctor first.
| Jinling hospital, affiliated to Medical school Nanjing University | Nanjing, Jiangsu, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06097962