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Study identifier: NCT06097637 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps

Condition: Pedunculated Colorectal Polyps · Haemorrhage  ·  Sponsor: Ningbo No. 1 Hospital

PhaseNA
Planned participants156
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Endoscopic resection of pedunculated polyps mainly focuses on how to prevent bleeding, and also needs to pay attention to the convenience of resection and the integrity of resection, which means that different endoscopic resection strategies should be adopted for pedunculated polyps with different pedicle sizes. The head larger than 20mm or pedicle larger than 5mm are defined as large pedunculated polyps, which are at greater risk of bleeding. Current guidelines recommend hot removal by snare following preoperative saline injection, ligation of the pedicle with a nylon ring or metal clip, depending on the size of the polyp head and pedicle. However, the use of snares and metal clamps does not appear to reduce delayed postoperative bleeding, and the technical requirements of nylon ligation are relatively high. Recent studies have found that Underwater endoscopic mucosal resection (UEMR) is also safe and effective for the treatment of large and medium colorectal sessile polyps. Therefore, it is still necessary to further explore new safe and effective endoscopic resection strategies and techniques.

This description comes directly from the study's public registry record.

Talk to the study team

Lei Xu  ·  +8613486659126  ·  xulei22@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

the First Affiliated Hospital of Ningbo UniversityNingbo, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06097637