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Study identifier: NCT06096974 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

Condition: Advanced Solid Tumors  ·  Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

PhasePhase 1
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will evaluate the safety, tolerability, drug levels, pharmacodynamic effects, and clinical activity of YL 17231 in patients with advanced solid tumors harboring mutations in KRAS, HRAS, or NRAS.

This description comes directly from the study's public registry record.

Talk to the study team

David S. Hong, MD  ·  (713) 563-1930  ·  dshong@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (3)

The Lindner Center for Research & Education at The Christ HospitalCincinnati, Ohio, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Huntsman Cancer Institute and Hospital, University of UtahSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06096974