● Recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Condition: Acquired Antithrombin Deficiency · Sponsor: Octapharma

PhasePhase 3

Planned participants120

Who can joinAll sexes, 18 Years to 85 Years

Healthy volunteersNo

About this study

The primary objective of this study is to evaluate the efficacy of two different doses of Atenativ, versus placebo, in restoring and maintaining heparin responsiveness in adult patients undergoing cardiac surgery necessitating cardiopulmonary bypass (CPB)

This description comes directly from the study's public registry record.

Talk to the study team

Cristina Solomon, MD · +41 79 585 90 42 · Cristina.Solomon@octapharma.com

Always discuss trial participation with your own doctor first.

Locations (27)

Stanford University School of Medicine	Stanford, California, United States	Recruiting
University of Miami	Miami, Florida, United States	Recruiting
Massachusetts General Hospital	Boston, Massachusetts, United States	Recruiting
Duke University Medical Center	Durham, North Carolina, United States	Recruiting
Atrium Health Wake Forest Baptist	Winston-Salem, North Carolina, United States	Recruiting
Cleveland Clinic	Cleveland, Ohio, United States	Not Yet Recruiting
The Ohio State University	Columbus, Ohio, United States	Recruiting
OU Health University of Oklahoma Medical Center	Oklahoma City, Oklahoma, United States	Recruiting
University of Texas Southwestern Medical Center	Dallas, Texas, United States	Recruiting
University Hospital Innsbruck	Innsbruck, Austria	Recruiting
Vienna General Hospital AKH, Medical University of Vienna	Vienna, Austria	Recruiting
Royal Columbian Hospital	New Westminster, British Columbia, Canada	Recruiting

+ 15 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06096116