Condition: Hepatorenal Syndrome · Sponsor: Methodist Health System
Hepatorenal syndrome (HRS) is a common cause of acute kidney injury (AKI) in patients with liver disease \[1\]. Increased activity and presence of vasodilators such as nitric oxide in cirrhotic patients leads to vasodilation, especially in the splanchnic circulation, resulting in hemodynamic changes that precipitate renal injury \[1\]. Patients may present with elevated serum creatinine (Cr), benign urine sediment, and low urine sodium \[1\].
This description comes directly from the study's public registry record.
Colette Ngo Ndjom, MS · 214-947-1281 · MHSIRB@mhd.com
Loretta W Bedell, MPH · 214-947-4680 · mhsirb@mhd.com
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| Liver Institute of Methodist Dallas Medical Center | Dallas, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06095440