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Study identifier: NCT06092554 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT)

Condition: Ventilator Associated Pneumonia  ·  Sponsor: University of Bari

PhaseNA
Planned participants186
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

PROACT study aims to resolve uncertainties to influence actual practice guidelines or public health policing regarding VAP prevention in ICU by using probiotics administration. Multi-trauma patients with a head injury OR stroke or brain haemorrhage patients without any sign of aspiration and lung infection will be enrolled and randomized to either placebo or probiotic treatment to assess if VAP and mortality can be reduced in the interventional group.

This description comes directly from the study's public registry record.

Talk to the study team

Alberto Corriero, MD  ·  +393280072443  ·  alberto.corriero@gmail.com

Filomena Puntillo, MD, PhD  ·  +390805594237  ·  filomena.puntillo@uniba.it

Always discuss trial participation with your own doctor first.

Locations (9)

Hospital ErasmeBrussels, BelgiumRecruiting
Regional General Hospital F. MiulliAcquaviva delle Fonti, BA, ItalyRecruiting
Intensive Care Unit, Policlinico di BariBari, BA, ItalyRecruiting
Azienda Ospedaliero Universitaria di Alessandria SS. Antonio e Biagio e Cesare ArrigoAlessandria, ItalyRecruiting
Ospedale Di VenereBari, ItalyRecruiting
AUSL Bologna Ospedale BellariaParma, ItalyRecruiting
Azienda Ospedaliero Universitaria di ParmaParma, ItalyRecruiting
Azienda Ospedaliera di PerugiaPerugia, ItalyRecruiting
Azienda ospedaliera Santa Maria di TerniTerni, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06092554