Condition: Heart Failure · Cardiomyopathy, Dilated · Cardiomyopathies · Sponsor: Imperial College London
One third of patients diagnosed with heart failure demonstrate left ventricular reverse remodelling and recovery of cardiac function following a period of medical therapy. The TRED-HF trial investigated the impact of therapy withdrawal in this cohort and found that 40% of patients relapsed within 6 months of stopping treatment. In this follow-on study, the investigators will investigate the safety of therapy withdrawal of sodium cotransporter 2 inhibitors (SGLT2i) and mineralocorticord receptor anatagonists (MRAs) in patients with a previous diagnosis of heart failure and recovered cardiac function, in a randomised controlled trial to assess whether this maintains remission in this population.
This description comes directly from the study's public registry record.
Saad Javed, MBChB · 02073528121 · tred2trial@imperial.ac.uk
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| Royal Brompton Hospital | London, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06091475