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Study identifier: NCT06090227 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AMPK-activation by Metformin in FSGS: AMP-FSGS

Condition: Focal Segmental Glomerulosclerosis  ·  Sponsor: Yale University

PhasePhase 1/Phase 2
Planned participants30
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The primary objective of this study is to determine whether extended-release MF (in addition to standard of care (S-o-C)) is superior to placebo in reducing podocyte injury and promoting podocyte survival by 6-months in Focal Segmental Glomerulosclerosis (FSGS).

This description comes directly from the study's public registry record.

Talk to the study team

Madhav C Menon, MD  ·  20373734507  ·  madhav.menon@yale.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Yale New Haven HospitalNew Haven, Connecticut, United StatesRecruiting
Mount Sinai HospitalNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06090227