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Study identifier: NCT06089486 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation

Condition: Cardiac Allograft Vasculopathy  ·  Sponsor: Ottawa Heart Institute Research Corporation

PhaseNA
Planned participants576
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cardiac allograft vasculopathy (CAV) is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. Surveillance for CAV is vital; however an ideal approach has not been established. The goal of this study is to assess whether noninvasive positron emission tomography (PET) based surveillance is non-inferior to invasive coronary angiography (ICA) surveillance.

This description comes directly from the study's public registry record.

Talk to the study team

Sharon Chih  ·  613-696-7000  ·  schih@ottawaheart.ca

Heather Ross  ·  heather.ross@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (5)

University of CalgaryCalgary, Alberta, CanadaNot Yet Recruiting
Mazankowski Alberta Heart InstituteEdmonton, Alberta, CanadaNot Yet Recruiting
University of Ottawa Heart InstituteOttawa, Ontario, CanadaRecruiting
Toronto-General Hospital - University Health NetworkToronto, Ontario, CanadaNot Yet Recruiting
Montreal Heart InstituteMontreal, Quebec, CanadaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06089486