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Study identifier: NCT06088589 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Speech-in-noise Perception in Autism and Fragile X

Condition: Autism Spectrum Disorder · Fragile X Syndrome  ·  Sponsor: Children's Hospital Medical Center, Cincinnati

PhaseNA
Planned participants60
Who can joinAll sexes, 15 Years to 35 Years
Healthy volunteersYes

About this study

The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact. The investigators are studying brain activation during speech-in-noise in autism and controls as well as individuals with Fragile X Syndrome. The main question\[s\] it aims to answer are: 1) How does the brain's response to background noise affect a person's ability to understand speech? 2) Can visual cues improve hearing in background noise? Participants will complete the following: * hearing tests * cognitive and behavioral measures * questionnaires about their symptoms * both passive and active hearing tasks while brain activity is recorded with a neuroimaging cap Results will be compared between individuals with autism with and without Fragile X Syndrome as well as individuals without autism.

This description comes directly from the study's public registry record.

Talk to the study team

Elizabeth Smith, PhD  ·  513-517-1383  ·  elizabeth.smith3@cchmc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cincinnati Children'S HospitalCincinnati, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06088589