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Study identifier: NCT06087926 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Apathy in Parkinson Disease TMS Study

Condition: Parkinson Disease  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants100
Who can joinAll sexes, 55 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to develop non-invasive brain stimulation targets for the treatment of apathy, or motivation problems, in Parkinson Disease. The main questions the study aims to answer are: 1. Does transcranial magnetic stimulation change effort task performance in Parkinson's Disease patients? 2. Is there a link between brain signals and apathy? Participants will * complete questionnaires and assessments * perform an effort task * have their brain activity recorded (EEG) * receive non-invasive brain stimulation (TMS) Researchers will compare two stimulation locations (experimental site and control site) to see if TMS of the experimental site has an effect on apathy. Participants will receive stimulation of both sites (during separate visits).

This description comes directly from the study's public registry record.

Talk to the study team

Cole Shumate  ·  919-445-0979  ·  shumatec@neurology.unc.edu

Miriam Sklerov, MD  ·  984-974-4401  ·  miri@email.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UNC-Chapel Hill, Cassidy LabChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06087926