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Study identifier: NCT06084286 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors

Condition: Advanced Solid Tumor  ·  Sponsor: Sichuan University

PhasePhase 1
Planned participants29
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Claudin18.2(CLDN18.2) is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in many solid tumors, especially in gastric cancer and pancreatic cancer. The CLDN18.2/PD-L1 dual-targeting CAR-T will be investigated in patients with CLDN18.2-positive advance solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Yao Zeng  ·  (+86)15982172735  ·  yao_zeng@stu.scu.edu.cn

Dan Li, PhD.  ·  (+86)13880025826  ·  lidan@wchscu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

West China Hospital, Sichuan UniversityChengdu, Sichuan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06084286