Condition: Osteoarthritis, Knee · Total Knee Arthroplasty · Chronic Postsurgical Pain · Sponsor: Vanderbilt University Medical Center
This is a prospective randomized controlled trial that will assess preoperative, perioperative, and long-term oxidative stress (OS); pain; and functional outcomes over a 12 month period and test the hypothesis that a potent antioxidant intervention (glycine + N-acetyl-cysteine(GlyNAC)) reduces oxidative stress and chronic post surgical pain (CPSP) in patients undergoing total knee arthroplasty (TKA).
This description comes directly from the study's public registry record.
Stephen Bruehl, Ph.D. · (615) 936-1821 · stephen.bruehl@vumc.org
Gail Mayo, RN · 615-936-1705 · gail.mayo@vumc.org
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| Vanderbilt University Medical Center | Nashville, Tennessee, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06083480