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Study identifier: NCT06082349 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema

Condition: Lymphedema, Secondary · Lymphedema of Upper Limb · Lymphedema, Lower Limb  ·  Sponsor: Maastricht University Medical Center

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this randomized controlled trial is to compare the effectiveness and cost-effectiveness of lymphaticovenous anastomosis (LVA) with sham surgery for patients suffering from unilateral cancer-related lymphedema in either the upper or lower extremity. It aims to answer whether LVA is more effective than sham surgery in terms of improvement in Lymph-ICF score. A total of 110 participants will be allocated randomly into two groups at a 1:1 ratio. The first group will receive lymphaticovenous anastomosis (LVA), while the second group will undergo sham surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Tanya Wolffenbuttel, MSc  ·  +31(0)433877481  ·  t.wolffenbuttel@erasmusmc.nl/tanya.wolffenbuttel@mumc.nl

Always discuss trial participation with your own doctor first.

Locations (3)

Radboud University Medical CenterNijmegen, Gelderland, NetherlandsRecruiting
Maastricht University Medical CenterMaastricht, Limburg, NetherlandsRecruiting
Erasmus University Medical CenterRotterdam, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06082349