Condition: Healthy Volunteer · Hidradenitis Suppurativa · Atopic Dermatitis · Sponsor: Leadingtac Pharmaceutical (Shaoxing) Co., Ltd.
LT-002-158 is an oral IRAK4 protein degrader being developed for the treatment of autoimmune disease and inflammation including Hidradenitis Suppurativa and Atopic Dermatitis. This first-in-human (FIH) study will characterize the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of a single ascending dose and multiple ascending doses of LT-002-158 in healthy volunteers. The effects of food on the pharmacokinetics of LT-002-158 will also be assessed in healthy volunteers.
This description comes directly from the study's public registry record.
Qian Chen, MD · +86-012-54036058 · qchen@shxh-centerlab.com
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| Shanghai Xuhui Distric Central Hospital | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06082323