Condition: Neurodevelopmental Disorders · Autism · Autism Spectrum Disorder · Sponsor: Holland Bloorview Kids Rehabilitation Hospital
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare. Sertraline, a selective serotonin reuptake inhibitor, has extensive evidence to support its use in children's and youth with anxiety but not within NDDs. More research is needed to confirm whether or not sertraline could help improve anxiety in children and youth with common and rare neurodevelopmental conditions. This is a pilot study, in which we plan to estimate the effect size of reduction in anxiety of sertraline vs. placebo. across rare and common neurodevelopmental disorders, and determine the best measure(s) to be used as a primary transdiagnostic outcome measure of anxiety, as well as diagnosis specific measures in future, larger-scale clinical trials of anxiety in NDDs.
This description comes directly from the study's public registry record.
Faiza Khawaja · 4164256220 · fkhawaja@hollandbloorview.ca
Always discuss trial participation with your own doctor first.
| Alberta Children's Hospital - University of Calgary | Calgary, Alberta, Canada | Recruiting |
| University of Alberta-Glenrose | Edmonton, Alberta, Canada | Recruiting |
| Dalhousie University - IWK Health Centre | Halifax, Nova Scotia, Canada | Active Not Recruiting |
| McMaster University | Hamilton, Ontario, Canada | Recruiting |
| Queen's University | Kingston, Ontario, Canada | Recruiting |
| University of Western Ontario, Lawson Health Research Institute | London, Ontario, Canada | Recruiting |
| Holland Bloorview Kids Rehabilitation Hospital | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06081348