Condition: Cannabis User · Sponsor: University Hospital, Lille
The endocannabinoid system (ECS) is a complex endogenous signaling system made up of transmembrane cannabinoid receptors (CB1 and CB2 receptors), their endogenous lipid-derived ligands (the endocannabinoids - eCBs), and enzymes for ligand biosynthesis and degradation. Interestingly, exercise increase plasma AEA, one of the most famous endocannabinoid. This increase could be involved in exercise-induced neurogenesis and other beneficial exercise adaptations. Chronic cannabis use is associated with alteration of ECS activity. The aim of the study is to compare ECS response to exercise between chronic cannabis users and non-users.
This description comes directly from the study's public registry record.
Olivier Cottencin, MD,PhD · 0320445962 · olivier.cottencin@chru-lille.fr
Francois-xavier Gamelin, PhD · 06.26.19.23.09 · francois-xavier.gamelin@univ-lille.fr
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| CHU Lille | Lille, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06081218