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Study identifier: NCT06080698 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

Condition: Gram-negative Bacteremia  ·  Sponsor: Johns Hopkins University

PhaseNA
Planned participants1030
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The Gram-negative bloodstream infection Oral Antibiotic Therapy trial (The GOAT Trial) is a multi-center, randomized clinical trial that hypothesizes that early transition to oral antibiotic therapy for the treatment of Gram-Negative BloodStream Infection (GN-BSI) is as effective but safer than remaining on intravenous (IV) antibiotic therapy for the duration of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Pranita D Tamma, MD, MHS  ·  410-614-1492  ·  tammap1@chop.edu

Sara E Cosgrove, MD, MS  ·  443-287-4570  ·  scosgro1@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (11)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting
Denver Health Hospital AuthorityDenver, Colorado, United StatesRecruiting
University of Maryland Medical CenterBaltimore, Maryland, United StatesRecruiting
Johns Hopkins University Hospital SystemsBaltimore, Maryland, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Rutgers-RWJ University HospitalNew Brunswick, New Jersey, United StatesRecruiting
Duke UniversityDurham, North Carolina, United StatesRecruiting
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting
Houston MethodistHouston, Texas, United StatesRecruiting
Carilion ClinicRoanoke, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06080698