Condition: Nephrotic Syndrome in Children · Sponsor: Mao Jianhua
Primary nephrotic syndrome accounts for approximately 90% of the total number of nephrotic syndrome in childhood and it is the most common glomerular disease in children. Although treatment with steroids is useful for primary nephrotic syndrome, proving to cause frequent relapse/steroid-dependent nephrotic syndrome after treatment and the usage of immunosuppressive agents has become a new choice for the treatment of such patients. This study is a prospective, multicenter, randomized，open-label clinical trial, evaluating the efficacy and safety of steroid combined with adrenocorticotrophic hormone（ACTH） to children who with frequently relapsing or steroid-dependent nephrotic syndrome, all we wish to obtain the proper drug choice and individualized treatment options for children with nephrotic syndrome.
This description comes directly from the study's public registry record.
jianhua Mao, MD · 0571-87061007 · maojh88@126.com
yi Xie · ylfx27@163.com
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| Tongji Hospital | Wuhan, Hubei, China | Recruiting |
| Nanjing Children's Hospital | Nanjing, Jiangsu, China | Recruiting |
| Kunming Children's Hospital | Kunming, Yunnan, China | Recruiting |
| Children's Hospital, Zhejiang University School of Medicine | Hangzhou, Zhejiang, China | Recruiting |
| Ningbo Women & Children's Hospital | Ningbo, Zhejiang, China | Recruiting |
| Yuying Childrens Hospital of Wenzhou Medical University | Wenzhou, Zhejiang, China | Recruiting |
| Children's Hospital affiliated to Capital Institute of Pediatrics | Beijing, China | Recruiting |
| Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06079788