Condition: Anaplastic Thyroid Cancer · Sponsor: Leiden University Medical Center
Anaplastic thyroid cancer (ATC) is an almost invariable lethal cancer in humans. Most patients present with a rapid progressive mass in the neck with progressive complaints like dyspnoea, dysphagia or pain. The risk of suffocation is the main reason for rapid surgical intervention, but we know from literature that an oncological resection with clear margins is seldomly achieved. Some patients deteriorate that fast after surgery that radiation therapy and/or chemotherapy is not feasible anymore. Patients with BRAF-mutated ATC already have shown to benefit from targeted BRAF/MEK inhibition. This study aims to increase the number of patients that undergo a successful R0 tumor resection after neo-adjuvant BRAF/MEK inhibitor treatment.
This description comes directly from the study's public registry record.
Ellen Kapiteijn, MD, PhD · 0031-71-5263486 · h.w.kapiteijn@lumc.nl
Saskia Luelmo, MD · 0031-71-5263464 · S.A.C.Luelmo@lumc.nl
Always discuss trial participation with your own doctor first.
| Ellen Kapiteijn | Leiden, South Holland, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06079333